Indianapolis Colts vs Kansas Chiefs Prediction: Kansas Chiefs are too strong for the Colts

On September 25, the Indianapolis Colts will host the Kansas City Chiefs in their first home game at Lucas Oil Stadium. Is there going to be a victor in this nail-biting matchup? Below, you'll find more details about the match and various betting options.

The Indianapolis Colts have not been having a good season. The Colts were not welcome in Jacksonville after Week 1's tie and subsequent 24-0 loss to the Jaguars. They get to play their first home game of the regular season in Lucas Oil Stadium, so this will be a plus for them. In most cases, being at home offers advantages. The Kansas City Chiefs are one of the best teams in the NFL, but when Indy takes the field at Lucas Oil Stadium, they will be hoping to make the match a difficult one for the visitors. We are anticipating a rout in this matchup between the Chiefs (2-0) and the Colts (1-3), as Kansas City is averaging 35.5 points per game, and Indianapolis is putting up a paltry 13.5. The Colts, however, should be able to raise their game since they will be playing in front of their home fans and benefiting from an increased level of encouragement.

The Chiefs opened the season with a 44-21 victory over the Cardinals. Subsequently, the Chiefs beat the Los Angeles Chargers 27-24 in a nail-biter. Patrick Mahomes has thrown for 595 yards, seven touchdowns, and no interceptions while completing 73% of his passes in the two games. Even though their defense was caught off guard last week, the Chiefs' offense has been very effective in their first two games of the 2022 NFL season. The City Chiefs, still a top contender for the Super Bowl, will need to shore up their defense if they want to extend their winning streak to three games. At Lucas Oil Stadium, the opposition should put up a good showing.

When you consider Kansas City is 2-0 and averaging 35.5 points per game, while Indianapolis is winless in its last two games, it's clear which team is in better shape. Furthermore, the Indys are 3-2 up against the City Chiefs when considering their recent combined performances. If the Indys want to keep their win streak against the Chiefs, they'll need to play better on offense and defense. If you want to bet in this match, the over is your best bet because both teams are weak.